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Table 2 Clinical comparison of the elderly and non-elderly patients with bacterial meningitis

From: Clinical characteristics and prognosis of acute bacterial meningitis in elderly patients over 65: a hospital-based study

Factors Elderly patients Non-elderly patients p
  (n = 87) (n = 174)  
Age (years); median (range) 71 (65 - 87) 48 (18 - 64)  
Gender    
Male 53 128 0.046*
Female 34 46  
Underlying condition    
Diabetes mellitus 30 38 0.036*
Liver cirrhosis 3 13 0.277
Alcoholism 4 12 0.590
End stage renal diseases 6 3 0.064
Malignancy 4 24a 0.032*
Spontaneous 39 52 0.019*
Community-acquired 44 67 0.084
Clinical presentation    
Fever 75 142 0.386
Altered consciousness 54 86 0.065
Seizure 26 41 0.294
Shock 10 17 0.671
Hydrocephalus 33 66 1.000
Brain abscess 7 18 0.659
Liver abscess 2 7 0.722
Positive blood culture 18 44 0.444
Leukocytosis 46 117 0.030*
Cerebrospinal fluid, median (IQR)    
White cell count (109/L) 0.32 (0.07, 0.87) 0.37 (0.08, 2.00)  
Glucose (mmol/L) 2.50 (0.77, 4.20) 2.53 (0.33, 4.13)  
Protein (g/L) 1.85 (0.88, 4.11) 1.93 (0.68, 5.39)  
Lactate (mmol/L) 8.25 (4.29, 15.51) 8.31 (4.41, 16.15)  
Prognosis    
Survived 53 126 0.067
Expired 34 48  
  1. *Fisher's exact test (p < 0.05); **Mann-Whitney U test (p < 0.05)
  2. Logistic regression analysis showed independent factor of "leukocytosis" (p = 0.018)
  3. IQR = inter-quartile range (25%, 75%)
  4. a Nasopharyngeal carcinoma (NPC) in 10 patients, lung cancer in 6 patients, breast cancer in 3 patients, hepatocellular carcinoma (HCC) in 2 patients, Hodgkin's lymphoma in 1 patient, plasma cell leukemia in 1 patient, buccal cancer in 1 patient, bladder in 1 patient and both NPC and HCC in 1 patient.