|
Factors
|
Elderly patients
|
Non-elderly patients
|
p
|
|---|
| |
(n = 87)
|
(n = 174)
| |
|---|
|
Age (years); median (range)
|
71 (65 - 87)
|
48 (18 - 64)
| |
|
Gender
| | | |
|
Male
|
53
|
128
|
0.046*
|
|
Female
|
34
|
46
| |
|
Underlying condition
| | | |
|
Diabetes mellitus
|
30
|
38
|
0.036*
|
|
Liver cirrhosis
|
3
|
13
|
0.277
|
|
Alcoholism
|
4
|
12
|
0.590
|
|
End stage renal diseases
|
6
|
3
|
0.064
|
|
Malignancy
|
4
|
24a
|
0.032*
|
|
Spontaneous
|
39
|
52
|
0.019*
|
|
Community-acquired
|
44
|
67
|
0.084
|
|
Clinical presentation
| | | |
|
Fever
|
75
|
142
|
0.386
|
|
Altered consciousness
|
54
|
86
|
0.065
|
|
Seizure
|
26
|
41
|
0.294
|
|
Shock
|
10
|
17
|
0.671
|
|
Hydrocephalus
|
33
|
66
|
1.000
|
|
Brain abscess
|
7
|
18
|
0.659
|
|
Liver abscess
|
2
|
7
|
0.722
|
|
Positive blood culture
|
18
|
44
|
0.444
|
|
Leukocytosis
|
46
|
117
|
0.030*
|
|
Cerebrospinal fluid, median (IQR)
| | | |
|
White cell count (109/L)
|
0.32 (0.07, 0.87)
|
0.37 (0.08, 2.00)
| |
|
Glucose (mmol/L)
|
2.50 (0.77, 4.20)
|
2.53 (0.33, 4.13)
| |
|
Protein (g/L)
|
1.85 (0.88, 4.11)
|
1.93 (0.68, 5.39)
| |
|
Lactate (mmol/L)
|
8.25 (4.29, 15.51)
|
8.31 (4.41, 16.15)
| |
|
Prognosis
| | | |
|
Survived
|
53
|
126
|
0.067
|
|
Expired
|
34
|
48
| |
- *Fisher's exact test (p < 0.05); **Mann-Whitney U test (p < 0.05)
- Logistic regression analysis showed independent factor of "leukocytosis" (p = 0.018)
- IQR = inter-quartile range (25%, 75%)
-
a Nasopharyngeal carcinoma (NPC) in 10 patients, lung cancer in 6 patients, breast cancer in 3 patients, hepatocellular carcinoma (HCC) in 2 patients, Hodgkin's lymphoma in 1 patient, plasma cell leukemia in 1 patient, buccal cancer in 1 patient, bladder in 1 patient and both NPC and HCC in 1 patient.
