Table 3 Current drug use in AD participants compared to controls
AD n = 187 | Control n = 200 | Difference* | 95%CI* | p-value* | |
|---|---|---|---|---|---|
Mean number of drugs ± SD | |||||
5.1 ± 3.6 | 2.9 ± 2.4 | 1.48 | 0.78 to 2.21 | < 0.001 | |
Mean number of antihypertensive drugs ± SD | |||||
1.4 ± 1.3 | 0.8 ± 0.9 | 0.28 | 0.012 to 0.538 | 0.040 | |
Participants using five drugs or more | |||||
n(%) | 90(48) | 46(23) | 0.19 | 0.076 to 0.289 | 0.001 |
antihypertensive drugs | |||||
n(%) | 128(68) | 101(50) | 0.039 | -0.074 to 0.153 | 0.50 |
anticholinergic drugs | |||||
n(%) | 43(23) | 12(6) | 0.161 | 0.080 to 0.243 | < 0.001 |
antidepressants | |||||
n(%) | 24(13) | 4(2) | 0.091 | 0.030 to 0.151 | 0.004 |
anxiolytic-hypnotic drugs | |||||
n(%) | 42 (22) | 15(8) | 0.090 | 0.008 to 0.172 | 0.032 |
inappropriate drugs** | |||||
n(%) | 69(37) | 22(11) | 0.193 | 0.097 to 0.288 | < 0.001 |
lipid lowering agents | |||||
n(%) | 53(28) | 69(35) | 0.000 | -0.111 to 0.112 | 0.99 |