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Table 5 Prevalence of the four most commonly used primary sedatives and drugs with sedation as a prominent adverse effect/containing a sedating component among residential care home residents with dementia

From: Sedative load of medications prescribed for older people with dementia in care homes

Variable Drug Name All residents Care Home
    1 2 3 4 5 6
   n = 115 n = 20 n = 17 n = 14 n = 22 n = 30 n = 12
Baseline         
Primary Sedatives [no.(%)] Promazine 5 (4.4) 2 (10.0) 0 1 (7.1) 1 (4.5) 1 (3.3) 0
  Temazepam 4 (3.5) 0 0 1 (7.1) 1 (4.5) 0 1 (8.3)
  Lorazepam 3 (2.6) 0 1 (5.9) 1 (7.1) 1 (4.5) 0 0
  Amitriptyline 3 (2.6) 2 (10.0) 1 (5.9) 0 0 0 0
Drugs with sedation as a prominent adverse effect/ Citalopram 18 (15.7) 6 (30.0) 2 (11.8) 1 (7.1) 1 (4.5) 5 (16.7) 3 (25.0)
containing a sedating component [no.(%)] Quetiapine 14 (12.2) 0 6 (35.3) 1 (7.1) 5 (22.7) 1 (3.3) 1 (8.3)
  Trazodone 12 (10.4) 0 0 0 11 (50.0) 1 (3.3) 0
  Fluoxetine 8 (7.0) 3 (15.0) 3 (17.6) 1 (7.1) 1 (4.5) 0 0
Timepoint 2   n = 112 n = 20 n = 17 n = 14 n = 22 n = 27 n = 12
Primary Sedatives [no.(%)] Promazine 5 (4.4) 2 (10.0) 0 1 (7.1) 1 (4.5) 1 (3.7) 0
  Temazepam 4 (3.6) 0 0 1 (7.1) 1 (4.5) 0 2 (16.7)
  Zopiclone 4 (3.6) 1 (5.0) 0 0 0 2(7.4) 1 (8.3)
  Lorazepam 3 (2.7) 0 0 1 (7.1) 1(4.5) 1 (3.7) 0
Drugs with sedation as a prominent adverse effect/ Citalopram 20 (17.9) 6 (30.0) 1 (5.9) 1 (7.1) 1 (4.5) 6 (22.2) 5 (41.7)
containing a sedating component [no.(%)] Trazodone 15(13.4) 0 0 3(21.4) 11 (50.0) 1 (3.7) 0
  Quetiapine 11 (9.8) 0 5 (29.4) 0 5 (22.7) 1 (3.7) 0
  Fluoxetine 9 (8.0) 3 (15.0) 3 (17.6) 1 (7.1) 1 (4.5) 1 (3.7) 0
Timepoint 3   n = 105 n = 19 n = 16 n = 14 n = 21 n = 25 n = 10
Primary Sedatives [no.(%)] Promazine 7 (6.7) 2 (10.0) 0 1 (7.1) 1 (4.8) 2 (8.0) 0
  Temazepam 3 (2.9) 0 0 1 (7.1) 1 (4.8) 0 1 (8.3)
  Zopiclone 3 (2.9) 0 0 0 0 2 (8.0) 0
  Lorazepam 3 (2.9) 2 (10.0) 0 1 (7.1) 1 (4.8) 1 (4.0) 0
Drugs with sedation as a prominent adverse effect/ Citalopram 18 (15.7) 5 (26.0) 0 2 (14.3) 1 (4.8) 5 (20.7) 5 (50.0)
containing a sedating component [no.(%)] Trazodone 15 (14.3) 0 0 3 (21.4) 10 (47.6) 1 (4.0) 1 (10.0)
  Quetiapine 9 (8.6) 0 4 (25.0) 0 4 (19.0) 1 (4.0) 0
  Fluoxetine 8 (7.6) 3 (15.8) 2 (12.5) 1 (7.1) 1 (4.8) 1 (4.0) 0
  1. BL - baseline, TP - time point