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Table 3 Use of regular medications, including sedative medications, by residential care home residents with dementia

From: Sedative load of medications prescribed for older people with dementia in care homes

Parameter

Care home at each time point

  

p - Value

 

1

  

2

  

3

  

4

  

5

  

6

     
 

BL

TP2

TP3

BL

TP2

TP3

BL

TP2

TP3

BL

TP2

TP3

BL

TP2

TP3

BL

TP2

TP3

BL

TP2

TP3

Number of residents (n)

20

20

19

17

17

16

14

14

14

22

22

21

30

27

25

12

12

10

   

Number of regular medications

                     

Mean

6.70

5.10

5.11

7.41

5.88

6.00

5.79

5.57

5.57

4.36

4.41

4.33

6.17

6.74

6.88

5.17

5.75

5.90

0.07

0.13

0.10

Range

1-10

1-8

1-8

2-18

2-11

2-11

1-10

0-13

0-13

0-8

0-9

1-9

0-10

0-13

0-13

0-12

0-12

1-12

   

Standard deviation

3.18

2.40

2.47

4.83

3.06

3.12

3.17

3.28

3.28

2.11

2.32

2.35

2.51

3.58

3.59

3.86

3.14

3.51

   

Polypharmacy (>4 medications) [no.(%)]

16 (80.0)

18 (90.0)

14 (73.6)

15 (88.2)

14 (82.3)

12 (75.0)

9 (64.2)

5 (35.7)

10 (74.1)

14 (63.6)

16 (72.7)

11 (52.4)

25 (83.3)

20 (74.0)

23 (92.0)

7 (58.3)

5 (41.7)

9 (90.0)

0.02

0.19

0.08

Sedative Load

                     

Mean

1.05

1.35

1.47

1.29

1.06

0.75

1.21

1.36

1.36

1.32

1.50

1.38

1.03

1.07

1.32

1.08

1.42

1.30

0.84

0.59

0.39

Range

0-5

0-5

0-5

0-6

0-3

0-3

0-4

0-4

0-5

0-3

0-3

0-3

0-3

0-4

0-4

0-3

0-3

0-2

   

Standard deviation

1.32

1.35

1.31

1.40

0.83

0.86

1.31

1.45

1.69

0.99

0.96

0.97

0.98

1.11

1.22

1.12

0.9

0.68

   

Antipsychotics [no.(%)]

2 (10.0)

4 (20.0)

5 (26.3)

7 (41.2)

6 (35.3)

4 (25.0)

2 (14.3)

1 (7.1)

1 (7.1)

7 (32.0)

6 (27.3)

5 (23.8)

3 (10.0)

3 (11.1)

4 (16.0)

2 (16.8)

1 (8.3)

0

0.02

0.17

0.04

Antidepressants [no.(%)]

11 (55.0)

12 (60.0)

11 (57.9)

9 (52.9)

6 (35.3)

4 (25.0)

5 (35.7)

8 (57.1)

9 (64.3)

15 (68.2)

14 (63.6)

13 (61.9)

10 (33.3)

11 (40.7)

11 (44.0)

4 (33.3)

6 (50.0)

6 (60.0)

0.29

0.41

0.35

Hypnotics and anxiolytics [no.(%)]

1 (5.0)

1 (5.0)

1 (5.3)

1 (5.9)

0

0

3 (21.4)

3 (21.4)

2 (14.3)

2 (9.1)

2 (9.1)

2 (9.5)

4 (13.3)

5 (18.5)

5 (20.0)

2 (16.7)

3 (25.0)

2 (20.0)

0.06

0.14

0.23

  1. BL - baseline, TP - time point