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Table 3 Use of regular medications, including sedative medications, by residential care home residents with dementia

From: Sedative load of medications prescribed for older people with dementia in care homes

Parameter Care home at each time point    p - Value
  1    2    3    4    5    6      
  BL TP2 TP3 BL TP2 TP3 BL TP2 TP3 BL TP2 TP3 BL TP2 TP3 BL TP2 TP3 BL TP2 TP3
Number of residents (n) 20 20 19 17 17 16 14 14 14 22 22 21 30 27 25 12 12 10    
Number of regular medications                      
Mean 6.70 5.10 5.11 7.41 5.88 6.00 5.79 5.57 5.57 4.36 4.41 4.33 6.17 6.74 6.88 5.17 5.75 5.90 0.07 0.13 0.10
Range 1-10 1-8 1-8 2-18 2-11 2-11 1-10 0-13 0-13 0-8 0-9 1-9 0-10 0-13 0-13 0-12 0-12 1-12    
Standard deviation 3.18 2.40 2.47 4.83 3.06 3.12 3.17 3.28 3.28 2.11 2.32 2.35 2.51 3.58 3.59 3.86 3.14 3.51    
Polypharmacy (>4 medications) [no.(%)] 16 (80.0) 18 (90.0) 14 (73.6) 15 (88.2) 14 (82.3) 12 (75.0) 9 (64.2) 5 (35.7) 10 (74.1) 14 (63.6) 16 (72.7) 11 (52.4) 25 (83.3) 20 (74.0) 23 (92.0) 7 (58.3) 5 (41.7) 9 (90.0) 0.02 0.19 0.08
Sedative Load                      
Mean 1.05 1.35 1.47 1.29 1.06 0.75 1.21 1.36 1.36 1.32 1.50 1.38 1.03 1.07 1.32 1.08 1.42 1.30 0.84 0.59 0.39
Range 0-5 0-5 0-5 0-6 0-3 0-3 0-4 0-4 0-5 0-3 0-3 0-3 0-3 0-4 0-4 0-3 0-3 0-2    
Standard deviation 1.32 1.35 1.31 1.40 0.83 0.86 1.31 1.45 1.69 0.99 0.96 0.97 0.98 1.11 1.22 1.12 0.9 0.68    
Antipsychotics [no.(%)] 2 (10.0) 4 (20.0) 5 (26.3) 7 (41.2) 6 (35.3) 4 (25.0) 2 (14.3) 1 (7.1) 1 (7.1) 7 (32.0) 6 (27.3) 5 (23.8) 3 (10.0) 3 (11.1) 4 (16.0) 2 (16.8) 1 (8.3) 0 0.02 0.17 0.04
Antidepressants [no.(%)] 11 (55.0) 12 (60.0) 11 (57.9) 9 (52.9) 6 (35.3) 4 (25.0) 5 (35.7) 8 (57.1) 9 (64.3) 15 (68.2) 14 (63.6) 13 (61.9) 10 (33.3) 11 (40.7) 11 (44.0) 4 (33.3) 6 (50.0) 6 (60.0) 0.29 0.41 0.35
Hypnotics and anxiolytics [no.(%)] 1 (5.0) 1 (5.0) 1 (5.3) 1 (5.9) 0 0 3 (21.4) 3 (21.4) 2 (14.3) 2 (9.1) 2 (9.1) 2 (9.5) 4 (13.3) 5 (18.5) 5 (20.0) 2 (16.7) 3 (25.0) 2 (20.0) 0.06 0.14 0.23
  1. BL - baseline, TP - time point