Skip to main content

Table 3 Comparison of %13C dose h- 1 curves and %13C cumulative excretion curves after oral administration of L-[1-13C] Phenylalanine in elderly groups (mean ± SD).

From: Clinical research on liver reserve function by 13C-phenylalanine breath test in aged patients with chronic liver diseases

Time Control (n = 38) Chronic Hepatitis B (n = 30) Cirrhosis (n = 55)
    Child-Pugh A (n = 19) Child-Pugh B (n = 28) Child-Pugh C (n = 8)
13CO2ER t
10 min 8.6 ± 1.4 8.2 ± 1.3 6.2 ± 1.3 a 4.3 ± 1.0 a, c 2.2 ± 0.7 a, c, d
20 min 13.9 ± 1.8 13.1 ± 1.3 8.9 ± 1.7 a 6.2 ± 0.9 a, c 3.7 ± 0.8 a, c, d
30 min 12.3 ± 1.6 11.8 ± 1.6 6.9 ± 1.2 a 5.1 ± 0.6 a, c 4.1 ± 0.3 a, c, e
45 min 6.8 ± 0.8 6.5 ± 0.7 5.4 ± 0.5 a 4.4 ± 0.5 a, c 3.9 ± 0.3 a, c, e
60 min 5.2 ± 0.5 5.1 ± 0.5 4.8 ± 0.5 a 3.9 ± 0.5 a, c 3.5 ± 0.3 a, c, e
90 min 4.5 ± 0.5 4.4 ± 0.5 4.0 ± 0.4 a 3.2 ± 0.5 a, c 2.8 ± 0.4 a, c, e
120 min 3.7 ± 0.5 3.6 ± 0.5 3.1 ± 0.4 a 2.4 ± 0.5 a, c 1.9 ± 0.6 a, c, e
13CCUM t
   CUM 10 min% 1.8 ± 0.3 1.7 ± 0.3 1.3 ± 0.3 a 0.9 ± 0.2 a, c 0.5 ± 0.1 a, c, d
   CUM 20 min% 4.7 ± 0.5 4.4 ± 0.4 3.1 ± 0.6 a 2.2 ± 0.3 a, c 1.2 ± 0.3 a, c, d
   CUM 30 min% 7.2 ± 0.6 6.9 ± 0.4 4.5 ± 0.7 a 3.2 ± 0.3 a, c 2.1 ± 0.3 a, c, d
   CUM 45 min% 8.6 ± 0.7 8.2 ± 0.5 5.7 ± 0.7 a 4.1 ± 0.4 a, c 2.9 ± 0.3 a, c, d
   CUM 60 min% 9.7 ± 0.7 9.3 ± 0.5 6.6 ± 0.8 a 4.9 ± 0.5 a, c 3.6 ± 0.3 a, c, d
   CUM 90 min% 10.6 ± 0.7 10.2 ± 0.5 7.5 ± 0.8 a 5.6 ± 0.5 a, c 4.2 ± 0.4 a, c, d
   CUM 120 min% 11.4 ± 0.8 10.9 ± 0.5 8.1 ± 0.8 a 6.1 ± 0.6 a, c 4.6 ± 0.4 a, c, d
  1. Note: Compare to control group, a P < 0.01, b P < 0.05;
  2. Compare with Child-Pugh A: c P < 0.01;
  3. Compare between Child-Pugh B and C, d P < 0.01, e P < 0.05