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Table 2 Comparison of liver function and blood test in elderly groups (mean ± SD).

From: Clinical research on liver reserve function by 13C-phenylalanine breath test in aged patients with chronic liver diseases

Indicatation Control (n = 38) Chronic Hepatitis B (n = 30) Cirrhosis (n = 55)
    Child-Pugh A (n = 19) Child-Pugh B (n = 28) Child-Pugh C (n = 8)
ALT (IU/L) 23.3 ± 7.3 90.3 ± 34.5a 42.2 ± 17.8 a 52.7 ± 27.8 a 46.3 ± 12.7 a
AST (IU/L) 16.1 ± 5.4 65.4 ± 17.1 a 33.2 ± 11.5 a 43.7 ± 19.8 a, c 51.9 ± 17.1 a, b
GGT (IU/L) 19.6 ± 6.7 23.5 ± 5.8 55.7 ± 33.1 a 59.1 ± 30.1 a 106.0 ± 70.8 a, b, d
ALP (IU/L) 97.3 ± 25.8 101.7 ± 32.2 114.0 ± 58.1 91.8 ± 18.4 c 147.5 ± 63.1 a, c, d
TBIL (μmol/L) 7.9 ± 2.4 9.7 ± 3.4 18.0 ± 5.8 a 22.6 ± 9.4 a, c 64.1 ± 10.5 a, b, d
DBIL (μmol/L) 2.0 ± 0.5 2.3 ± 0.6 7.4 ± 2.7 a 7.3 ± 2.9 a 38.8 ± 2.5 a, b, d
ALB (g/L) 39.9 ± 2.9 39.7 ± 1.9 36.1 ± 2.4 a 30.6 ± 2.1 a, b 25.6 ± 1.1 a, b, d
PT(s) 11.7 ± 1.0 12.1 ± 0.8 14.4 ± 1.5 a 16.7 ± 2.9 a, b 20.9 ± 2.2 a, b, d
HB (g/L) 13.1 ± 1.2 13.2 ± 1.1 11.0 ± 1.1 a 8.5 ± 1.3 a, b 7.9 ± 1.6 a, b
PLT (109/L) 193.3 ± 46.2 175.5 ± 43.2 146.5 ± 41.5 a 91.6 ± 22.5 a, b 90.3 ± 9.9 a, b
  1. Note: ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutamyltransferase; ALP, alkaline phosphatase; TBIL, serum total bilirubin; DBIL, serum direct bilirubin; ALB, serum albumin; PT, prothrombin time; HB, haemoglobin; PLT, platelet count
  2. Compare to control group, a P < 0.01;
  3. Compare with Child-Pugh A: b P < 0.01, c P < 0.05;
  4. Compare between Child-Pugh B and C, d P < 0.05