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Table 1 Research questions for the acute care setting in descending order of priority.

From: Identifying research priorities on infections in older adults: proceedings of an interdisciplinary workshop

1. In frail older adults, does the use of a critical care pathway for management of
  pneumonia reduce hospital stay and improve health-related quality of life?
2. For older adults over the age of 85 years, does admission to an intensive care unit for
  sepsis reduce mortality?
3. In hospitalized older adults, what are the modifiable risk factors for nosocomial
  pneumonia?
4. What are the barriers to implementation of a hospital-based pneumococcal vaccination
  program for older adults?
5. In older adults admitted to hospital with respiratory symptoms, how common is
  infection with influenza?
6. Does a computer-based learning intervention improve nurses' knowledge about
  infection control precautions for hospitalized older adults?
7. Compared to intravenous therapy, are highly bioavailable oral antibiotics effective in
  treating older adults admitted to hospital with pneumonia?
8. In older adults with nosocomial pneumonia, what are the most
  important predictors of excess length of stay?
9. Compared to usual care, do oral feeding programs for hospitalized older adults lead to
  earlier discharge?
10. What is the effectiveness of nursing-based strategies to reduce infection in hospitalized
  high risk older adults?
11. In hospitalized older adults, do swallowing evaluations and diet modifications reduce
  pneumonia and other respiratory infections?
12. Does early mobilizing of hospitalized older adults reduce the overall infection rate?
13. Amongst older adults admitted to hospital from nursing homes, what is the
  prevalence of colonization with multi-resistant bacteria and how common is
  transmission of these multi-resistant bacteria to other hospitalized patients?
14. In older adults, does early discharge from hospital reduce the risk for infection?
15. For older adults admitted to hospital with nursing home acquired pneumonia, does the
  addition of empiric anti-pseudomonal antibiotic coverage to standard therapy reduce
  mortality?
16. For specific nosocomial infections, are older adults treated with a longer duration of
  antibiotics than younger patients?
17. For older adults started on antibiotic therapy, does concurrent administration of an oral
  Lactobacillus preparation decrease the rate of Clostridium difficile-associated
  diarrhea?
18. In older adults hospitalized for pneumonia, what is the natural history of functional
  status?
19. Does a care path for urinary care reduce duration and frequency of urinary
  catherization in older hospitalized patients?
20. In older adults, does the administration of supplemental oxygen during joint
  replacement surgery decrease the risk of infection?