Table 1 Inclusion and exclusion criteria

• Systematic reviews and meta-analyses: mean age ≥ 65 years

• Original studies: at least 80% of participants ≥65 years old

OR

• Subgroup analysis reporting on participants ≥65 years

• Intervention: thiazide or thiazide-like diuretics

• Condition: hypertension

• Clinical relevant outcomes

• Studies focusing only on acute/short term conditions

• Studies evaluating only surrogate endpoints (like blood pressure)

• The following publication types:

⋅ Editorials

⋅ Opinion papers

⋅ Case reports, case series

⋅ Narrative reviews

⋅ Letters

⋅ Qualitative studies