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Table 1 Characteristics of subjects according to MetS (N = 695)

From: The Klotho gene G-395A polymorphism and metabolic syndrome in very elderly people

Characteristics

Total (N = 695)

Men (N = 220)

Women (N = 475)

MetS (N = 65)

Non-MetS (N = 630)

P

MetS (N = 7)

Non-MetS (N = 213)

P

MetS (N = 58)

Non-MetS (N = 417)

P

Age (years)

93.3 ± 3.0

93.6 ± 3.2

0.532

92.7 ± 2.8

93.3 ± 3.1

0.606

93.4 ± 3.1

93.7 ± 3.3

0.505

Women (%)

89.2

66.2

<0.001

-

-

-

-

-

-

BMI (kg/m2)

22.3 ± 3.3

18.9 ± 3.6

<0.001

23.8 ± 4.5

19.6 ± 3.8

0.004

22.2 ± 3.1

18.6 ± 3.4

<0.001

WC (cm)

87.8 ± 5.2

76.5 ± 7.9

<0.001

92.1 ± 2.5

78.3 ± 7.3

<0.001

87.2 ± 5.2

75.6 ± 8.1

<0.001

SBP (mm Hg)

156 ± 18.2

138 ± 23.3

<0.001

152.9 ± 11.1

137.6 ± 20.3

0.049

156.8 ± 18.9

139.3 ± 24.7

<0.001

DBP (mm Hg)

78.4 ± 15.1

72.0 ± 11.6

<0.001

77.1 ± 7.6

73.1 ± 11.2

0.345

78.5 ± 15.8

71.4 ± 11.7

0.001

FPG (mmol/L)

5.1 ± 2.1

4.4 ± 1.3

<0.001

7.4 ± 2.8

4.5 ± 1.5

<0.001

4.9 ± 1.8

4.3 ± 1.2

0.022

TC (mom/L)

4.5 ± 1.0

4.6 ± 2.0

0.930

4.1 ± 1.1

5.3 ± 2.6

0.874

4.5 ± 1.0

4.2 ± 0.8

<0.001

TG (mmol/L)

2.0 ± 1.1

1.2 ± 0.6

<0.001

1.9 ± 1.0

1.0 ± 0.4

<0.001

2.1 ± 1.2

1.2 ± 0.6

<0.001

LDL-C (mmol/L)

2.6 ± 0.7

2.2 ± 0.6

<0.001

2.5 ± 0.7

2.1 ± 0.5

0.079

2.6 ± 0.7

2.3 ± 0.6

<0.001

HDL-C (mmol/L)

1.4 ± 0.5

1.6 ± 0.8

0.020

1.2 ± 0.3

1.5 ± 0.7

0.179

1.4 ± 0.5

1.7 ± 0.8

0.019

SUA (mmol/L)

342.4 ± 83.4

316.3 ± 88.3

0.023

394.7 ± 31.4

350.9 ± 87.6

0.189

336.0 ± 85.6

298.6 ± 83.4

0.002

Smoking habits* (%)

35.9

43.6

0.237

85.7

69.7

0.361

29.8

30.4

0.934

Alcohol habits** (%)

14.1

27.2

0.022

28.6

39.0

0.576

12.3

21.3

0.113

Exercise habits*** (%)

36.9

41.0

0.524

14.3

42.3

0.139

39.7

40.3

0.920

Klotho G-395A Genotypes

GG (%)

81.5

69.2

0.046

85.7

72.8

0.447

81.0

67.4

0.034

GA (%)

18.5

28.9

 

14.3

27.2

 

19.0

29.7

 

AA (%)

0

1.9

 

0

0

 

0

2.9

 
  1. Abbreviations: BMI body mass index, DBP diastolic blood pressure, FPG fasting plasma glucose, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, MetS metabolic syndrome, SBP systolic blood pressure, SUA serum uric acid, TC total cholesterol, TG triglyceride, WC waist circumference
  2. *Indicates those who were a smoker at the time of the interview
  3. **Indicates those who still drank alcohol at least once a day at the time of the interview
  4. ***Indicates those who still did some physical exercise at least 3 time per week at the time of the interview