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Table 3 Characteristics and results of included food and drink modification, swallowing intervention, eating or drinking assistance and social support interventions

From: Effectiveness of interventions to directly support food and drink intake in people with dementia: systematic review and meta-analysis

Study

Design

Setting, Intervention type

No.

Dementia stage

Dementia type

Effect on Nutrition / hydration status

Intake effect

Quality & other outcomes

Duration

Swallowing interventions

 Bautmans 2008 Belgium [56]

RCT

Nursing home. Cervical spine mobilization to help dysphagia

15

Severe

AD

NR

NR

↑ Dysphagia limit

1 week

 Germain 2006 Canada [57]

RCT

Long term care facility. Dysphagia diet

I = 8

C = 9

NR

AD &

others

↑ Weight

↑ E intake

NR

12 weeks

 Robbins 2008 USA [58, 102104]

RCT

Hospitals & nursing homes.

1. Nectar-thick or

2. Honey-thick consistency fluids

3. Chin-tuck position

Nectar 133,

Honey 123,

Chin-tuck

259

Various

NR

 

NR

→ Aspiration pneumonia incidence (for thickened vs chin-tuck)

3 months

Food modification

 Beck 2010 Denmark [31, 101]

RCT

Elderly nursing home residents. ONS, Gratin diet, swallowing problem management, exercise and oral care vs usual care

I = 54

C = 55

NR

NR

BMI

↑ Weight

→ E-intake

↑ Protein intake

→ Cognitive performance

→ ADL

11 weeks

 Boffelli 2004 Italy [33]

CCT

(BA)

Dementia unit. Diet & environment modification, feeding assistance and supplements

29

Severe

Various

→ BMI

→ weight

↑ Albumin

NR

NR

18 months

 Jean 1997 USA [59]

CCT

(BA)

Nursing home.

Finger food menu

12

NR

AD &

others

? Weight loss arrest

NR

? Eating independence

6 months

 Keller 2003 Canada [63, 105]

CCT

Long term care facilities. Individualised food service, food modification, education and dietitian time

I = 33

C = 49

NR

AD &

others

↑ weight

NR

NR

21 months

 Kenkmann 2010 UK [64, 106]

RCT

6 Care homes. Dining environment & menu changes

I = 57,

C = 48

NR

NR

→ Weight,

→ BMI,

→ Hydrated

NR

→ Enjoyment

of food/drink

1 year

 Salas-Salvado 2005 Spain [61]

RCT

Geriatric institutions.

Meal replacement with commercial

lyophilised supplement

I = 15

C = 23

Severe

AD

↑ Weight

↑ Serum albumin

→ E intake

→ Nutritional risk

→ Eating behaviour

→ Mortality

→ Cognitive parameters

3 months

 Soltesz 1995 USA [60]

CCT

(BA)

Alzheimer’s Care Centre.

Finger food provision

43

NR

AD

→ Weight

↑ Proportion food eaten

NR

6 months

 Young 2005 Canada [54, 62, 100]

RCT

Nursing home.

High CHO dinners

I = 15

C 19

NR

AD

NR

↑ E intake

NR

21 days

Eating or drinking assistance interventions

 Boffelli 2004 Italy [33]

CCT

(BA)

Dementia unit, diet & environment modification, feeding assistance and supplements

29

Severe

Various

→ BMI

→ Weight

↑ Albumin

NR

NR

18 months

 Simmons 2001 USA [65, 107]

CCT

Nursing Homes. Staff assistance, prompting, food/drink service and exercise

I = 48

C = 15

NR

NR

→ Serum osmolality

→ BUN: creatinine ratio

→ Food

& fluid intake

NR

32 weeks

 Simmons 2008 USA [66]

RCT

Skilled nursing homes. Either meal time or between meal feeding assistance

I = 35

C = 34

NR

NR

? BMI,

? Weight

E intake

NR

24 weeks

 Simmons 2010a USA [50]

RCT

Long-term care facilities. Between meal supplements & assistance vs usual care

I1 = 18

C 20

NR

NR

→ Weight

→ E intake

NR

6 weeks

 Simmons 2010b USA [50]

RCT

Long-term care facilities. Between meal snacks & assistance vs usual care

I2 = 25

C = 20

NR

NR

→Weight

→ E intake

NR

6 weeks

 Wong 2008 New Zealand [67]

CCT

(BA)

Short stay assessment unit.Individual mealtime assistance

7

NR

NR

BMI

E intake

NR

12 weeks

Studies with a strong social element around eating/drinking

 Altus 2002 USA [68]

CCT

(BA)

Locked dementia unit.

Family-style meals −/+ staff training

5

Mod-

severe

AD &

others

NR

NR

? Resident Participation in mealtime tasks

? Appropriate communication

? Praise statements

? Staff satisfaction with resident participation

5 days each period

 Charras 2010 France [69]

CCT

Dementia units in nursing homes.

Shared mealtime with staff

I = 8

C = 10

Severe

AD

Weight

NR

? Autonomy

? Quality of interactions

? Food quality

6 months

 Huang 2009 Taiwan [70]

CCT

(BA)

Older person care facility,

Reminiscence cooking therapy

12

Mild-mod

NR

NR

NR

→ MMSE

↑ Happiness

→ Communication

? Participation

8 weeks

 Santo Pietro 1998 USA [71]

CCT

Dementia unit within a nursing home.

Breakfast club (communication therapy)

I = 20

C = 20

Mild-mod

AD

NR

NR

↑ Interest & involvement

↑ Communication

12 weeks

  1. ↑ indicates statistically significant increase; ↓ indicates statistically significant reduction; → indicates no statistically significant effect; ? indicates unclear whether effect was statistically significant. Statistical significance of all effects were checked by reviewers where data were available, and reviewers results used when they differed from the original paper.
  2. AD Alzheimer’s disease, ADL activities of daily living, BA before-after, BMI body mass index, CCT controlled clinical trial, CG control group, CHO Carbohydrate, E energy, IG intervention group, NR not reported, ONS oral nutritional supplement, RCT randomised controlled trial, vs versus