Insights into the clinical management of the syndrome of supine hypertension – orthostatic hypotension (SH-OH): The Irish Longitudinal Study on Ageing (TILDA)

Table 4 Contribution of MOH-3 towards OI in the presence of potential confounders

Full sample	B	Std. error	P	Odds ratio	95% wald confidence interval for odds ratio
Full sample	B	Std. error	P	Odds ratio	Lower	Upper
MOH-3	0.39	0.08	<0.001	1.47	1.25	1.73
Female sex	−0.17	0.06	0.008	0.84	0.74	0.96
N05C (hypnotics, sedatives)	0.60	0.17	<0.001	1.83	1.31	2.54
Heart attack	0.47	0.16	0.004	1.59	1.16	2.19
3 or more chronic diseases	0.18	0.08	0.023	1.19	1.02	1.39
Any IADL disability	0.32	0.16	0.048	1.38	1.00	1.90
Age	−0.02	0.00	<0.001	0.98	0.98	0.99
MMSE	−0.04	0.02	0.043	0.96	0.93	1.00
Subsample ≥70 years old	B	Std. error	P	Odds ratio	95% wald confidence interval for odds ratio
Subsample ≥70 years old	B	Std. error	P	Odds ratio	Lower	Upper
C08C (peripheral CCB)	−0.53	0.22	0.015	0.59	0.39	0.90
N03A (antiepileptics)	0.91	0.44	0.036	2.50	1.06	5.86
3 or more chronic diseases	0.38	0.15	0.011	1.46	1.09	1.95

Dependent variable: phasic OI. Binary logistic response, forward conditional procedure. Predictors entered: female sex, polypharmacy, C01A (cardiac glycosides), C01B (antiarrhythmics), C07A (beta blockers), C03 (diuretics), C09A (ACE-i), C09C (ARA), C08C (peripheral CCB), C08D (cardiac CCB), C02C (alpha blockers), C01D (cardiac vasodilators), C04A (peripheral vasodilators), N03A (antiepileptics), N05A (antipsychotics), N05B (anxiolytics), N05C (hypnotics, sedatives), N06A (antidepressants), hypertension, angina, heart attack, heart failure, diabetes, stroke¸ TIA, abnormal heart rhythm, Parkinson’s disease, three or more chronic diseases, any IADL disability, age, MOH-3, MMSE.

ISSN: 1471-2318