Table 1 Characteristics of included studies

Rondanelli et al. 2010 [40]

84.9

1.67 g/d EPA; 0.83 g/d DHA

Paraffin oil

8 weeks

46

Liquid

^a Bechoua et al. 2003 [29]

75.6

30 mg/d EPA 150 mg/d DHA

Sunflower oil

6 weeks

20

Capsules

^b Vericel et al. 1999 [30]

Gruenwald et al. 2009 [42]

62.3

0.6 g/d EPA/DHA

Glucosamine sulfate

26 weeks

177

Capsules

^a Van de Rest et al. 2009 [36]

69.8

1.8 g/d EPA/DHA (high-dose); OR 0.4 g/d EPA/DHA (low dose)

High-oleic sunflower oil

26 weeks

302

Capsules

^b Bouwens et al. 2009 [39]

^c Van de Rest et al. 2008 [37]

^d Van de Rest et al. 2008 [38]

Querques et al. 2009 [41]

72.7

0.72 g/d EPA; 0.48 g/d DHA

Usual care

26 weeks

38

Unclear

^a Thies et al. 2001 [31]

55-75

0.7 g/d DHA; OR 0.72 g/d EPA; 0.28 g/d DHA

α-linolenic acid, γ-linolenic acid, OR arachidonic acid

12 weeks

46

Capsules

^b Thies et al. 2001 [32]

^a Vedin et al. 2010 [33]

74

0.6 g/d EPA; 1.72 g/d DHA

Corn oil

52 weeks

174

Capsules

^b Vedin et al. 2008 [34]

^c Freund-Levi et al. 2006 [35]

Smith et al. 2011 [45]

71

1.86 g/d EPA; 1.5 g/d DHA

Corn oil

8 weeks

15

Capsules

Fakhrzadeh et al. 2010 [43]

74.8

180 mg/d EPA; 120 mg/d DHA

26 weeks

124

Capsules

Holguin et al. 2005 [44]

76.5

2 g/d total marine triglycerides; each 1 g containing 83.2% EPA/DHA

Soy oil

26 weeks

52

Capsules