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Table 3 Odds ratios (and 95% CIs) for exposures, adjusted† for covariates and stratified by surgical procedure.

From: Risk of venous thromboembolism after total hip and knee replacement in older adults with comorbidity and co-occurring comorbidities in the Nationwide Inpatient Sample (2003-2006)

 

HIP PROCEDURES

KNEE PROCEDURES

Exposure

VTE yes

VTE no

OR†

CIs

VTE yes

VTE no

OR

CIs

No Comorbidity

410

57403

1.00

(ref)

1458

131682

1.00

(ref)

CVD vs.

3

567

0.71

(0.23-2.23)

21

1335

1.42

(0.92-2.20)

CAD vs.

68

9064

0.98

(0.76-1.28)

257

19760

1.19

(1.04-1.37)

CHF vs.

25

1072

3.08

(2.05-4.65)

73

2673

2.47

(1.95-3.14)

Diabetes vs.

47

7735

0.85

(0.63-1.15)

282

26458

0.96

(0.85-1.10)

COPD vs.

60

7929

1.06

(0.81-1.39)

273

16563

1.49

(1.31-1.70)

CAD and CHF vs.

12

719

2.11

(1.18-3.78)

33

1645

1.86

(1.30-2.60)

CAD & COPD vs.

16

1715

1.25

(0.75-2.06)

52

3314

1.44

(1.09-1.90)

Diabetes & CAD vs.

18

2302

1.05

(0.65-1.69)

47

7108

0.61

(0.45-0.81)

Diabetes & COPD vs.

9

1172

1.09

(0.56-2.11)

36

3652

0.89

(0.64-1.24)

All other combinations

34

2691

1.69

(1.19-2.40)

111

6767

1.49

(1.23-181)

Age 65-69

163

23242

1.00

(ref)

734

62629

1.00

(ref)

Age 70-74 vs. Age 65-69

167

24721

0.96

(0.77-1.19)

751

62857

1.01

(0.91-1.12)

Age 75-79 vs. Age 65-69

172

23144

1.05

(0.84-1.30)

649

53929

1.00

(0.90-1.12)

Age ≥80 vs. Age 65-69

200

21262

1.30

(1.05-1.60)

509

41542

0.99

(0-89-1.11)

Females

411

58081

1.00

(ref)

1746

143315

1.00

(ref)

Males

291

34287

1.21

(1.04-1.41)

897

77642

0.94

(0.87-1.02)

Total observations

702

92369

  

2643

220957

  
  1. †Associations adjusted in multivariate logistic regression for each comorbidity exposure as compared with the group with none of the listed comorbidities or co-occurring comorbidities. All association were adjusted for age group and sex. We also assessed race, insurance status, hospital surgical volume, obesity, bi-laterality (two primary procedures during the same surgery) and hypercoagulable state but deleted them from the final model for lack of confounding. Abbreviations: CAD = coronary artery disease, CHF = congestive heart failure, COPD = chronic obstructive pulmonary disease, CVD = cerebrovascular disease.